Engineering Mechanics

International Conference

Proceedings Vol. 7 (2001)


INŽENÝRSKÁ MECHANIKA 2001

ENGINEERING MECHANICS 2001

NATIONAL CONFERENCE WITH INTERNATIONAL PARTICIPATION
May 14 – 17, 2001, Svratka, Czech Republic
;
Editors: Alena Poživilová and Jan Masák

Copyright © 2001 Institute of Thermomechanics, Academy of Sciences of the Czech Republic, Prague

ISBN 80-885918-64-1 (printed)
ISSN 1805-8248 (printed)
ISSN 1805-8256 (electronic)

list of papers scientific commitee

Computer modelling of effect of transversal tubules on excitation-contraction coupling in cardiac cells (basic study)
Pásek M., Christé G., Šimurda J.
pages 196 - +6p, full text

The transverse tubular system (T-system) of cardiac muscle is a structure that allows rapid propagation of excitation into the cell interior. As suggested in many resent experimental works it could have a significant effect on cardiac cell function induced by the accumulation or the depletion of ions in restricted tubular space. The aim of our work was to design a mathematical model of electrical activity of cardiac cell including a quantitative description of T-system function and to explore the physiological significance of T-system in excitation-contraction coupling quantitatively.


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